Comparison Between Vaginal Misoprostol Gel and Oral Misoprostol Solution in Induction of Labor

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

February 26, 2025

Primary Completion Date

August 31, 2025

Study Completion Date

September 30, 2025

Conditions
Cervical Ripening and Induction of Labor
Interventions
DRUG

Vaginal misoprostol

the vaginal misoprostol solution will be prepared by complete crushing of one misoprostol 200 µg tablet into powder then adding the powder into a clean urine specimen cup then adding 20 cc of KY gel measured by a 20 ml syringe then mix the contents together to ensure adequate distribution of the powder , each patient will receive only 2.5cc of the mixture vaginally (inserted into the posterior fornix,) by using medical 3ml syringes equal to 25 mcg misoprostol 4 hourly according to International Federation of Gynecology and Obstetrics (FIGO2023) and remain recumbent for 10-20 minutes

DRUG

Oral misoprostol solution (OMS)

the solution will be prepared by dissolving one 200 µg tablet in 200 ml of tap water , each member will receive 25 cc misoprostol solution equal to 25 mcg misoprostol 2 hourly according to International Federation of Gynecology and Obstetrics (FIGO2023)

Trial Locations (1)

Unknown

Ain Shams university Maternity Hospital, Cairo

All Listed Sponsors
lead

Hagar Muhammad Abdulfattah Muhammad

OTHER