Perimenstrual Symptoms and Emotional Dysregulation in Autism

NANot yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

March 1, 2028

Study Completion Date

September 1, 2028

Conditions
Autism Spectrum DisorderBorderline Personality Disorder BPD
Interventions
OTHER

Semi-structured interviews SCID

"Structured Clinical Interview for DSM-5 Personality Disorder (SCID) :~The SCID is a 90-item semi-structured interview, covering all 10 categories of personality disorder as described in the DSM-5. Each item is rated on a three-point scale: absent, subclinical level and present."

OTHER

Self-report questionnaires

Participants will complete a battery of self-report questionnaires, assessing emotional dysregulation (including SRD, the primary endpoint), childhood adversity, anxiety, depression, and premenstrual symptoms.

OTHER

Cognitive assessment

"Cognitive assessment, coupled with the recording of physiological parameters (Biopac).~Participants will complete a battery of neuropsychological tests targeting emotional processes. These tests will make it possible to evaluate the hot component of executive functioning, i.e. specifically involved in the processing of socio-emotional information. Autobiographical verbal fluences and the emotional Hayling test will be used to measure initiation and inhibition processes, respectively."

OTHER

Momentary Ecological Assessment (EMA)

A momentary ecological evaluation protocol will be proposed between visits V1 and V4 in order to assess the emotional and symptomatic dynamics in a context of daily life. During two menstrual cycles, subjects will be invited, via their smartphone, to take daily semi-random readings (indicated by SMS) of their subjective (4 times/day), but also spontaneous emotional experiences

All Listed Sponsors
lead

University Hospital, Strasbourg, France

OTHER

NCT06871345 - Perimenstrual Symptoms and Emotional Dysregulation in Autism | Biotech Hunter | Biotech Hunter