Early Neuromodulation in Traumatic Brain Injury

Anodal transcranial electrical stimulation (A-tES) is a widely used and well tolerated non-invasive electrical stimulation paradigm that promotes adaptive neuroplasticity and may prevent or reduce pathological sequela following brain injury. It has been used in a wide variety of neurologic and psychiatric disorders for cognitive and motor rehabilitation.

Sham comparator consist of A-tES in the beginning and end of stimulation block but no stimulation during the actual stimulation period.