52
Participants
Start Date
March 15, 2025
Primary Completion Date
December 31, 2025
Study Completion Date
March 1, 2026
Extraperitoneal(transvaginal paracervical sentinel lymphadenectomy) group lymphadenectomy
The procedure begins with a vaginal incision in the lateral vaginal fornices (on both sides), which is then extended to allow placement of the V-NOTES apparatus. By identifying an appropriate cleavage plane, the obturator fossa is accessed to excise the obturator lymph nodes. Following this, an anterior colpotomy is performed to access the vesicocervical space, and a posterior colpotomy is made to open the rectouterine pouch. The V-NOTES apparatus is then placed to continue with the hysterectomy and bilateral salpingo-oophorectomy (BSO).
Transperitoneal lymphadenectomy
In this arm, patients will undergo transperitoneal lymphadenectomy with V-NOTES. The procedure begins with anterior and posterior colpotomies, followed by placement of the V-NOTES apparatus. Hysterectomy is performed first, followed by peritoneal dissection and lymph node excision.
RECRUITING
Gazi Yasargil Training And Research Hospital, Diyarbakır
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
OTHER