Comparison of Transvaginal Paracervical and Transperitoneal Approaches in Lymphadenectomy During v-NOTES Surgery for Patients Diagnosed With Endometrial Cancer

NARecruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

March 15, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

March 1, 2026

Conditions
Endometrial CancerLymphadenectomySentinel Lymph Node BiopsyMinimally Invasive Surgical ProceduresNatural Orifice Transluminal Endoscopic Surgery
Interventions
PROCEDURE

Extraperitoneal(transvaginal paracervical sentinel lymphadenectomy) group lymphadenectomy

The procedure begins with a vaginal incision in the lateral vaginal fornices (on both sides), which is then extended to allow placement of the V-NOTES apparatus. By identifying an appropriate cleavage plane, the obturator fossa is accessed to excise the obturator lymph nodes. Following this, an anterior colpotomy is performed to access the vesicocervical space, and a posterior colpotomy is made to open the rectouterine pouch. The V-NOTES apparatus is then placed to continue with the hysterectomy and bilateral salpingo-oophorectomy (BSO).

PROCEDURE

Transperitoneal lymphadenectomy

In this arm, patients will undergo transperitoneal lymphadenectomy with V-NOTES. The procedure begins with anterior and posterior colpotomies, followed by placement of the V-NOTES apparatus. Hysterectomy is performed first, followed by peritoneal dissection and lymph node excision.

Trial Locations (1)

21090

RECRUITING

Gazi Yasargil Training And Research Hospital, Diyarbakır

All Listed Sponsors
lead

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

OTHER