NCT06870838 - Neuroinflammation in FTLD | Biotech Hunter

Enrollment

110

Participants

Timeline

Start Date

July 25, 2023

Primary Completion Date

August 1, 2025

Study Completion Date

August 31, 2026

Conditions

Frontotemporal Lobar Degeneration (FTLD)Corticobasal Syndrome(CBS)Primary Progressive Aphasia(PPA)Progressive Supranuclear Palsy(PSP)Behavioral Variant Frontotemporal Dementia (bvFTD)

Interventions

DIAGNOSTIC_TEST

7T MRI scan

MRI-scanning of the brain using a 7T MRI scanner

DIAGNOSTIC_TEST

CSF

CSF collection via lumbar puncture

DIAGNOSTIC_TEST

Blood withdrawal

Blood is collected by doing a blood withdrawal

DIAGNOSTIC_TEST

Neuropsychological assessment

Tests for memory, language, attention, executive functions, praxis, social cognition, visuoconstructive skills

DIAGNOSTIC_TEST

Clinical measures

Medical history, neurological assessment, neuropsychiatric inventory

Trial Locations (2)

Unknown

Leiden University Medical Center, Leiden

3015GE

Erasmus MC, Rotterdam