Comparative Study of Antegrade Versus Retrograde Cerebral Perfusion in Acute Type A Aortic Dissection: A Prospective Study

NACompletedINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

June 22, 2020

Primary Completion Date

January 1, 2023

Study Completion Date

March 1, 2023

Conditions
Acute Type A Aortic Dissection
Interventions
PROCEDURE

Antegrade Cerebral Perfusion via Axillary Artery

In antegrade cerebral perfusion (ACP), patients underwent cannulation of the right axillary artery using an interposition Dacron graft (7 mm) connected to a cardiopulmonary bypass (CPB) circuit. During surgery, ACP delivered oxygenated blood flow directly into the brain arteries to maintain cerebral protection during the period of deep hypothermic circulatory arrest (DHCA), enabling the surgical team to perform the distal aortic anastomosis safely.

PROCEDURE

Retrograde Cerebral Perfusion via Superior Vena Cava

In retrograde cerebral perfusion (RCP), cannulation of the superior vena cava (SVC) was performed to deliver blood flow in reverse direction during deep hypothermic circulatory arrest (DHCA). This method aimed to provide cerebral protection by supporting cerebral metabolism during the surgical repair of acute Type A aortic dissection.

Trial Locations (1)

41522

Department of Cardiothoracic Surgery, Faculty of Medicine, Suez Canal University., Suez Canal

All Listed Sponsors
lead

Yusuf Shieba

OTHER

NCT06870513 - Comparative Study of Antegrade Versus Retrograde Cerebral Perfusion in Acute Type A Aortic Dissection: A Prospective Study | Biotech Hunter | Biotech Hunter