1,600
Participants
Start Date
September 22, 2025
Primary Completion Date
December 1, 2027
Study Completion Date
December 1, 2027
MFGM-RUTF (milk fat globule membrane ready-to-use therapeutic food)
MFGM whey protein/fat concentrate powder used in place of skim milk powder in peanut paste-based ready-to-use therapeutic food meeting Codex Alimentarius specifications. There will be 10g of MFGM-containing whey protein/fat concentrate powder per 100g of MFGM-RUTF. Other ingredients and amounts per 100g: 9.5g rice flour, 5g whey permeate, 18.5g palm oil, 31g peanut paste, 22.1g sugar, 2.9g micronutrient mix, 1g fish oil.
S-RUTF (standard ready-to-use therapeutic food)
Standard peanut paste-based ready-to-use therapeutic food made with skim milk powder meeting Codex Alimentarius specifications. This RUTF is modeled on the most widely used recipe worldwide, containing per 100g: 19.5g skim milk powder, 9.3g palm oil, 7g canola oil, 31.3g peanut paste, 28g sugar, 1g soy flakes, 1g hydrogenated vegetable oil, and 2.9g micronutrient mix.
Amoxicillin
Oral amoxicillin tablets twice per day for 7 days dosed based on weight
Sulfadoxine (12.5 mg)/Pyrimethamine (250 mg)
Malaria chemoprophylaxis, dosed by weight, to be given every month during SAM treatment
RECRUITING
Bandajuma, Bandajuma
RECRUITING
Bandasuma, Bandasuma
RECRUITING
Bendu Malen, Bendu Malen
RECRUITING
Gbondapi, Gbondapi
RECRUITING
Jendema, Jendema
RECRUITING
Potoru, Potoru
RECRUITING
Sahn Malen, Sahn Malen
RECRUITING
Taninahun, Taninahun
RECRUITING
Zimmi, Zimmi
RECRUITING
Static, Pujehun
Project Peanut Butter
OTHER
Ministry of Health and Sanitation, Sierra Leone
OTHER_GOV
Arla Food Ingredients Group P/S
UNKNOWN
The Danish Dairy Research Foundation, Denmark
OTHER
Washington University School of Medicine
OTHER