NCT06868992View on ClinicalTrials.gov

Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA

Not yet recruitingOBSERVATIONAL

Enrollment

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

February 29, 2028

Study Completion Date

February 29, 2028

Conditions

Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated SteatohepatitisSleeve GastrectomyGastric Bypass Surgery

Interventions

PROCEDURE

Bariatric surgery (Sleeve Gastrectomy or Gastric Bypass)

Patients undergoin bariatric surgery with simultaneous liver biopsy to analyze MAMs alterations in liver and PBMCs. Follow-up assessments at 6 and 12 months.

Trial Locations (2)

69003

Hospices Civils de Lyon - Hôpital Edouard Herriot, Lyon

69495

Centre Hospitalier Lyon Sud, Endocrinologie, Diabète et nutrition, Pierre-B&nite

All Listed Sponsors

lead

Hospices Civils de Lyon

OTHER

NCT06868992 - Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA | Biotech Hunter | Biotech Hunter