Reducing Pain With Methadone and Ketamine in Liver Transplant

PHASE4RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

July 1, 2026

Study Completion Date

September 1, 2026

Conditions
Liver Transplantation
Interventions
DRUG

Methadone

Participants in this group will receive one bolus dose of intravenous Methadone and Ketamine at the start of operation

DRUG

ketamine

Participants in this group will receive one bolus dose of intravenous Methadone and Ketamine at the start of operation

DRUG

Hydromorphone

Participants in this group will receive standard of care for pain with either intravenous fentanyl and/or hydromorphone boluses during the procedure

DRUG

fentanyl

Participants in this group will receive standard of care for pain with either intravenous fentanyl and/or hydromorphone boluses during the procedure

Trial Locations (2)

01805

NOT_YET_RECRUITING

Lahey Hospital and Medical Center, Burlington

RECRUITING

Lahey Hospital and Medical Center, Burlington

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Lahey Clinic

OTHER

NCT06868589 - Reducing Pain With Methadone and Ketamine in Liver Transplant | Biotech Hunter | Biotech Hunter