Neuronavigation-assisted Stereotactic Puncture With Tenecteplase for Acute Intracerebral Hemorrhage

PHASE3RecruitingINTERVENTIONAL
Enrollment

732

Participants

Timeline

Start Date

April 25, 2025

Primary Completion Date

March 1, 2027

Study Completion Date

September 1, 2027

Conditions
Deep Intracerebral Hemorrhage (ICH)
Interventions
PROCEDURE

Neuronavigation-assisted Stereotactic Minimally Invasive Puncture Combined with Tenecteplase

Neuronavigation-assisted stereotactic minimally invasive puncture will enhances catheter placement precision, reducing complications and improving hematoma evacuation and neurological outcomes. TNK, a third-generation thrombolytic will offers advantages over alteplase (rt-PA), including a longer half-life for rapid bolus administration and effective thrombolytic effects to dissolve clots and promote hematoma clearance.

DRUG

Standard medical treatment

The standard medical treatment for this group of patients will be provided according to the optimal care standards defined by the American Heart Association (AHA) guidelines for intracerebral hemorrhage management

Trial Locations (1)

100000

RECRUITING

Beijing Tiantan Hospital, Beijing

All Listed Sponsors
lead

Beijing Tiantan Hospital

OTHER