Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

October 4, 2016

Primary Completion Date

June 10, 2024

Study Completion Date

June 10, 2024

Conditions

AnesthesiaTooth Extraction

Interventions

DRUG

Midazolam Hydrochloride

Short-acting sedative. Benzodiazepine. Gamma-aminobutyric acid (GABA) inhibitor

DRUG

Fentanyl

Synthetic opioid drug used as an analgesic.

DRUG

Ketamine

General Anesthetic. N-methyl-D-aspartate (NMDA) receptor agonist

DRUG

Propofol injection

General Anesthetic. GABA receptor modulator and calcium channel blocker

DRUG

Nitrous oxide

Modulates a wide range of ligand-gated ion channels and inhibits NMDA receptor-mediated currents

Trial Locations (1)

NYCHHC - Jacobi Medical Center and North Central Bronx Hospital, The Bronx

All Listed Sponsors

lead

Albert Einstein College of Medicine

OTHER

NCT06867068 - Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery | Biotech Hunter | Biotech Hunter