NCT06865079 - 53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee | Biotech Hunter

Enrollment

270

Participants

Timeline

Start Date

May 9, 2025

Primary Completion Date

May 25, 2027

Study Completion Date

June 15, 2027

Conditions

Osteoarthritis (OA) of the Knee

Interventions

DRUG

TPX-100 200mg, Once weekly for 4 weeks

"TPX-100 (200 mg per dose) will be administered once-weekly (Week 1, 2, 3 \& 4) to a single target knee of the subject for 4 injections.~TPX-100 can be administered by conventional methods such as subcutaneous or intra-articular injection."

OTHER

PBS

PBS / placebo for intra-articular injection administered once-weekly (Week 1, 2, 3 and 4) to a single target knee of the subject for 4 injections

Trial Locations (33)

16602

RECRUITING

University Orthopedics Center, Altoona

16801

RECRUITING

University Orthopedics Center, State College

27103

NOT_YET_RECRUITING

Center for Clinical Research, Winston-Salem

30060

RECRUITING

Drug Studies of America, Marietta

32751

RECRUITING

K2 Medical Research, Maitland

33135

RECRUITING

Wellness Research Center, Miami

33173

RECRUITING

Well Pharma Medical Research, Miami

33196

RECRUITING

Las Mercedes Medical Research, Miami

37909

NOT_YET_RECRUITING

AMR Knoxville, Knoxville

40509

RECRUITING

AMR Lexington, Lexington

55905

RECRUITING

Mayo Clinic (Rochester), Rochester

64114

RECRUITING

AMR Kansas City, Kansas City

66160

RECRUITING

University of Kansas Medical Center, Kansas City

70605

NOT_YET_RECRUITING

Accurate Clinical Research Inc., Lake Charles

73102

RECRUITING

Hightower Clinical, Oklahoma City

75006

RECRUITING

Legent Orthopedic Hospital, Carrolton

76021

RECRUITING

Texas Orthopedic Specialist, Bedford

77089

NOT_YET_RECRUITING

Accurate Clinical Research, Houston

77401

RECRUITING

First Surgical Hospital, Bellaire

77521

RECRUITING

Accurate Clinical Research, LLC, Baytown

78229

NOT_YET_RECRUITING

Endeavor Clinical Trials, San Antonio

84107

RECRUITING

CenExel, Salt Lake City

RECRUITING

Wasatch Clinical Research, Salt Lake City

85260

RECRUITING

Elite Clinical Network, Scottsdale

85704

RECRUITING

Noble Clinical Research, Tucson

87102

RECRUITING

Albuquerque Clinical Trials, Albuquerque

89030

RECRUITING

Las Vegas Clinical Trials, North Las Vegas

90602

RECRUITING

Medvin Clinical Research Center, Whittier

91042

RECRUITING

Medvin Clinical Research Center, Tujunga

91722

RECRUITING

Medvin Clinical Research, Covina

92024

RECRUITING

CORE Orthopaedic Medical Center, Encinitas

92518

RECRUITING

Medvin Clinical Research Center, Riverside

92647

RECRUITING

Marvel Clinical Research (Elite Clinical Network), Huntington Beach