NCT06862115View on ClinicalTrials.gov

The Effect of Discontinuation of Renin Angiotensin System Inhibitors on the Perioperative Myocardial Injury in Adult Patients Undergoing Colorectal Cancer Surgery

PHASE3RecruitingINTERVENTIONAL

Enrollment

156

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2025

Conditions

Myocardium; InjuryPerioperative/Postoperative ComplicationsAngiotensin-Converting-Enzyme Inhibitor

Interventions

DRUG

ACE-I and/or ARB antihypertensive treatment

When the ACE-I and/or ARB duration of action is ≥24 hours, the drug will be stopped 48 hours prior to surgery. All other ACE-I and/or ARB will be stopped 24 hours before surgery.

Trial Locations (1)

Unknown

RECRUITING

Cairo university hospitals, Cairo

All Listed Sponsors

lead

Kasr El Aini Hospital

OTHER