Comparison Volume-controlled Ventilation, Pressure-controlled Volume-guaranteed Ventilation, and Pressure-controlled Ventilation During Gynecologic Laparoscopic Surgery in the Steep Trendelenburg Position

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 1, 2021

Primary Completion Date

August 1, 2021

Study Completion Date

September 1, 2021

Conditions
Mechanical VentilationLaparoscopic Gynecologic SurgeryPeak Inspiratuar Pressure
Interventions
DEVICE

Device: Volume-Controlled Ventilation (VCV)

Tidal volume: 8 mL/kg of ideal body weight Respiratory rate adjusted to maintain an end-tidal CO₂ (EtCO₂) level of 30-35 mmHg Inspiratory-expiratory ratio: 1:2 PEEP: 5 cmH₂O Mechanical ventilation was provided using a Datex-Ohmeda Avance Anesthesia Machine (GE Healthcare, USA) Measurements were taken at four predefined time points (T1-T4)

DEVICE

Device: Pressure-Controlled Ventilation (PCV)

Initial peak inspiratory pressure adjusted to deliver a tidal volume of 8 mL/kg of ideal body weight Respiratory rate adjusted to maintain an end-tidal CO₂ (EtCO₂) level of 30-35 mmHg Inspiratory-expiratory ratio: 1:2 PEEP: 5 cmH₂O Mechanical ventilation was provided using a Datex-Ohmeda Avance Anesthesia Machine (GE Healthcare, USA) Measurements were taken at four predefined time points (T1-T4)

DEVICE

Device: Pressure-Controlled Volume-Guaranteed Ventilation (PCV-VG)

Pressure-controlled mode with volume guarantee to maintain a tidal volume of 8 mL/kg of ideal body weight Respiratory rate adjusted to maintain an end-tidal CO₂ (EtCO₂) level of 30-35 mmHg Inspiratory-expiratory ratio: 1:2 PEEP: 5 cmH₂O Mechanical ventilation was provided using a Datex-Ohmeda Avance Anesthesia Machine (GE Healthcare, USA) Measurements were taken at four predefined time points (T1-T4)

Trial Locations (1)

Unknown

Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul

All Listed Sponsors
lead

Dr. Lutfi Kirdar Kartal Training and Research Hospital

OTHER_GOV

NCT06861959 - Comparison Volume-controlled Ventilation, Pressure-controlled Volume-guaranteed Ventilation, and Pressure-controlled Ventilation During Gynecologic Laparoscopic Surgery in the Steep Trendelenburg Position | Biotech Hunter | Biotech Hunter