Silicone Effect on Corneal Endothelium and Corneal Biomechanics Using Corvis ST

CompletedOBSERVATIONAL
Enrollment

80

Participants

Timeline

Start Date

May 1, 2022

Primary Completion Date

October 1, 2024

Study Completion Date

December 31, 2024

Conditions
Silicon Oil Effect on CorneaCorneal Biomechanics
Interventions
DIAGNOSTIC_TEST

Corvis ST

"Corvis ST is used to assess corneal biomechanical changes following vitrectomy with silicone oil tamponade, specifically:~Corneal stiffness and elasticity using the Stress-Strain Index (SSI) Corneal deformation response via Deformation Amplitude (DA)"

DIAGNOSTIC_TEST

Conrneal endothelial cell density

"The study evaluates the impact of silicone oil tamponade on corneal endothelial cell density (ECD) in patients undergoing vitrectomy for retinal detachment. The intervention involves:~Preoperative and Postoperative Assessments at 1, 3, and 6 months to monitor changes in ECD.~Specular Microscopy to measure ECD (cells/mm²), coefficient of variation (CV) in cell size, and hexagonality (% of hexagonal cells)."

Trial Locations (2)

Unknown

Fayoum University Hospital, Al Fayyum

Misr University For Science and Technology, Giza

All Listed Sponsors
lead

Beni-Suef University

OTHER