Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar

NANot yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

October 30, 2028

Conditions
BurnsContracture ScarSurgical Injury
Interventions
PROCEDURE

Full Thickness Skin Graft (FTSG)

Full thickness skin in FTSGs are harvested by different means by surgeon preference and standard of care. Typically an area of skin with matching color and texture to the site which needs reconstruction is identified from a hidden and/or non-cosmetic area and collected via excision. After excision the donor site is closed and the graft is thinned by using a scalpel or scissors to remove excess fat or other soft tissues from the deep surface before being placed in the donor site.

PROCEDURE

Base of wound fat graft with Split Thickness Skin Graft (STSG) Reconstruction (Autologous Layered Composite Grafting).

Autologous Layered Composite Grafting consists of the layered strategy of simultaneous fat and skin grafting. Fat is harvested by minimally invasive liposuction and applied directly to the wound base without any chemical or biologic processing. Skin is harvested as a split thickness skin graft by dermatome and applied over the layer of adipose tissue.

Trial Locations (2)

15219

Mercy Hospital, Pittsburgh

Presbyterian Hospital, Pittsburgh

All Listed Sponsors
collaborator

Armed Forces Institute of Regenerative Medicine

FED

lead

University of Pittsburgh

OTHER

NCT06857435 - Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar | Biotech Hunter | Biotech Hunter