NCT06856369View on ClinicalTrials.gov

Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic Periodontitis

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 22, 2025

Primary Completion Date

February 14, 2026

Study Completion Date

September 30, 2027

Conditions
Alveolar Bone Loss Associated Chronic Periodontitis
Interventions
PROCEDURE

Platelet rich fibrin

sub-gingival administration of platelet rich fibrin following open flap surgery

DRUG

Metformin hydrochloride powder

subgingival administration of 1% Metformin Hydrochloride gel with platelet rich fibrin following open flap surgery

DRUG

alendronate sodium powder

subgingival administration of 1% Alendronate gel with platelet rich fibrin following open flap surgery

Trial Locations (1)

04408

Islamabad Medical & Dental College, Islamabad

All Listed Sponsors
collaborator

Islamabad Medical and Dental College

OTHER

lead

Bahria University

OTHER

NCT06856369 - Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic Periodontitis | Biotech Hunter | Biotech Hunter