Prospective, Multicentre, Randomized, Blind, Parallel-controlled Clinical Trial Evaluating the Efficacy and Safety of Recombinant Collagen Gel for Correcting Moderate to Severe Nasolabial Wrinkles

NAEnrolling by invitationINTERVENTIONAL
Enrollment

244

Participants

Timeline

Start Date

January 10, 2025

Primary Completion Date

October 1, 2025

Study Completion Date

December 31, 2026

Conditions
Nasolabial Fold Wrinkles
Interventions
DEVICE

Recombinant collagen gel

The test device uses a recombinant collagen gel developed by Shaanxi Juzi Biotechnology Co., Ltd., which is different from other designs. The main components of recombinant collagen gel are recombinant collagen, disodium hydrogen phosphate, potassium dihydrogen phosphate, sodium chloride, water for injection, after the injection, collagen can occupy a place at the injection site to improve the visual aging caused by soft tissue loss, wrinkles and depressions, and the special manufacturing process can ensure that the gel has smoothness and ductility, which helps to achieve a smooth and natural appearance, effectively and gradually improve wrinkles and plump cheeks.

DEVICE

collagen implant agent

1\. After the product is injected into the skin, the collagen implant forms a soft mesh structure through condensation, which can make up for skin defects. 2. After implantation of this product, the connective tissue cells around the implantation site will grow into the collagen network structure and gradually form a bionic structure similar to normal tissue. 3. This product is absorbable and degradable. The collagen implant will be gradually decomposed by protease in the body, and the pressure, elongation and hierarchy of the implant site tissue will affect the final degradation and duration.

Trial Locations (1)

Unknown

The Seventh Medical Center of the Chinese People's Liberation Army General Hospital, Beijing

All Listed Sponsors
lead

Shaanxi Giant Biotechnology Co., Ltd

INDUSTRY