780
Participants
Start Date
April 7, 2025
Primary Completion Date
October 31, 2027
Study Completion Date
January 31, 2028
Daily prone position sessions
Prone position sessions will be extended at least 16 hours, but no longer than 24 hours. Prone sessions will be repeated if PaO2/FiO2 ratio decreases to \< 150 after returning to supine position within the first 7 days after randomization. The extension of repeated prone sessions will follow the same criteria.
Prolonged prone position sessions
Prone position sessions will be extended at least 48 hours AND until PaO2/FiO2 ratio is ≥ 200, but no longer than 120 hours. Prone sessions will be repeated if PaO2/FiO2 ratio decreases to \< 150 after returning to supine position within the first 7 days after randomization. The extension of repeated prone sessions will follow the same criteria.
RECRUITING
Hospital Guillermo Grant Benavente, Concepción
RECRUITING
Complejo Asistencial Dr. Victor Ríos Ruiz, Los Ángeles
RECRUITING
Hospital de Quilpué, Quilpué
RECRUITING
Clínica Las Condes, Santiago
RECRUITING
Hospital Clínico UC Christus, Santiago
RECRUITING
Hospital Clínico Universidad de Chile, Santiago
Hospital do Coracao
OTHER
Fundacion Clinica Valle del Lili
OTHER
Fondo Nacional de Desarrollo Científico y Tecnológico, Chile
OTHER_GOV
Pontificia Universidad Catolica de Chile
OTHER