Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression

NANot yet recruitingINTERVENTIONAL
Enrollment

280

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

November 30, 2029

Study Completion Date

December 31, 2029

Conditions
Late Life Depression (LLD)Depression - Major Depressive DisorderDepressive Disorder, Treatment-ResistantMood Disorders
Interventions
DEVICE

TBS

Repetitive transcranial magnetic stimulation (rTMS) is a form of non-invasive neurostimulation that uses focused magnetic field pulses to directly stimulate cortical neurons. Theta burst stimulation (TBS) is a briefer form of patterned rTMS that has been shown to be effective against major depressive disorder. Each treatment will consist of either 1) cTBS of right DLPFC followed by iTBS of left DLPFC; or 2) iTBS of left DLPFC.

Trial Locations (2)

M4N 3M5

Sunnybrook Health Sciences Centre, Toronto

M6J 1H1

Centre for Addiction and Mental Healh, Toronto

All Listed Sponsors
collaborator

Sunnybrook Health Sciences Centre

OTHER

lead

Centre for Addiction and Mental Health

OTHER

NCT06854367 - Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression | Biotech Hunter | Biotech Hunter