NCT06851663View on ClinicalTrials.gov

Trop2-targeted immunoPET Imaging of Solid Tumors

NARecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

December 23, 2024

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Solid TumorSolid CarcinomaUroepithelial CarcinomaBladder CancerProstate CancerLung CancerNasopharyngeal CancerLiver CancerCholangiocarcinomaOvarian CancerCervical CancerEndometrial CancerThyroid CancerHead and Neck Cancer
Interventions
DRUG

[68Ga]Ga-NOTA-T4

Enrolled patients will receive 0.05-0.1 mCi/kg of \[68Ga\]Ga-NOTA-T4. ImmunoPET/CT imaging will be acquired 1-2 hours after \[68Ga\]Ga-NOTA-T4 injection.

DRUG

[68Ga]Ga-NOTA-RT4

Enrolled patients will receive 0.05-0.1 mCi/kg of \[68Ga\]Ga-NOTA-RT4. ImmunoPET/CT imaging will be acquired 1-2 hours after \[68Ga\]Ga-NOTA-RT4 injection.

DRUG

[18F]F-RESCA-T4

Enrolled patients will receive 0.05-0.1 mCi/kg of \[18F\]F-RESCA-T4. ImmunoPET/CT imaging will be acquired 1-2 hours after \[18F\]F-RESCA-T4 injection.

DRUG

[18F]F-RESCA-RT4

Enrolled patients will receive 0.05-0.1 mCi/kg of \[18F\]F-RESCA-RT4. ImmunoPET/CT imaging will be acquired 1-2 hours after \[18F\]F-RESCA-RT4 injection.

Trial Locations (1)

200127

RECRUITING

Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai

All Listed Sponsors
lead

RenJi Hospital

OTHER