Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

NARecruitingINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

January 6, 2025

Primary Completion Date

December 17, 2025

Study Completion Date

December 17, 2025

Conditions
Open Angle Glaucoma
Interventions
PROCEDURE

Nasal 180° Selective Laser Trabeculoplasty (SLT)

The Nasal 180° Selective Laser Trabeculoplasty (SLT) will be performed on the right eye. As per standard procedure, the laser will initially be set at 0.8 mJ (or 0.4 mJ for heavily pigmented TM). The energy level will then be adjusted in 0.1 mJ increments: increased until micro-bubble formation is observed or decreased if bubbles are noted. The desired endpoint is the production of a few fine 'champagne bubbles' every 2-3 laser spots. Larger gas bubbles and trabecular meshwork blanching will require the operator to titrate the power downwards in 0.1 mJ increments. Prophylactic IOP lowering and anti-inflammatory drops will be left to physician preference.

PROCEDURE

Inferior 180° Selective Laser Trabeculoplasty (SLT)

The Inferior 180° Selective Laser Trabeculoplasty (SLT) will be performed on the right eye. As per standard procedure, the laser will initially be set at 0.8 mJ (or 0.4 mJ for heavily pigmented TM). The energy level will then be adjusted in 0.1 mJ increments: increased until micro-bubble formation is observed or decreased if bubbles are noted. The desired endpoint is the production of a few fine 'champagne bubbles' every 2-3 laser spots. Larger gas bubbles and trabecular meshwork blanching will require the operator to titrate the power downwards in 0.1 mJ increments. Prophylactic IOP lowering and anti-inflammatory drops will be left to physician preference.

Trial Locations (2)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

NS B3H 2Y9

RECRUITING

Eye Care Centre, Victoria General Hospital, Halifax

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT06851546 - Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree | Biotech Hunter | Biotech Hunter