NCT06848465View on ClinicalTrials.gov

LDRT Combined With Immunochemotherapy for Colorectal Cancer With Liver Metastasis

PHASE1RecruitingINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

February 28, 2025

Primary Completion Date

August 30, 2026

Study Completion Date

November 30, 2027

Conditions
Colorectal CancerLiver MetastasisLDRT
Interventions
RADIATION

Low Dose Radiotherapy

10 Gy in 5 fractions, 15 Gy in 3 fractions, 20 Gy in 10 fractions respectively in three Cohorts from Day1

RADIATION

Short course Radiotherapy

25 Gy in 5 fractions from Day1

DRUG

XELOX

Oxaliplatin: 130mg/m2 IV Q3W on day 1 of each cycle. Capecitabine: 1000mg/m2 Q3W Dose of 1000mg/m2 on day 1-14 of each cycle.

DRUG

Tislelizumab

200mg IV Q3W on day 1 of each cycle.

Trial Locations (2)

400042

RECRUITING

Army Medical Center, Chongqing

ACTIVE_NOT_RECRUITING

Daping Hospital, Army Medical University, Chongqing

All Listed Sponsors
lead

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

OTHER