NCT06847412View on ClinicalTrials.gov

The Effectiveness of Two Distinct Ventilation Strategies Escalating Positive End Expiratory Pressure (PEEP) and Lung Recruitment Maneuvers in Improving Oxygenation

NAActive, not recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 30, 2025

Primary Completion Date

July 27, 2025

Study Completion Date

July 27, 2025

Conditions
HypoxemiaCOPD
Interventions
DEVICE

Escalating PEEP

Typically, an initial PEEP of 5 cm H₂O, then PEEP is increased in 2-3 cm H₂O increments while monitoring the patient's response (oxygenation, hemodynamics, and lung compliance).

DEVICE

Sustained inflation

Set the ventilator to CPAP mode and increase the pressure to 30 cm H2O for 30 s.

Trial Locations (1)

11111

Ain Shams university, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT06847412 - The Effectiveness of Two Distinct Ventilation Strategies Escalating Positive End Expiratory Pressure (PEEP) and Lung Recruitment Maneuvers in Improving Oxygenation | Biotech Hunter | Biotech Hunter