Lemborexant for the Treatment of Residual Insomnia in Major Depressive Disorder (MDD)

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

February 28, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

September 30, 2026

Conditions
Major Depressive Disorder(MDD)Insomnia Comorbid to Psychiatric Disorder
Interventions
DRUG

Lemborexant

Dayvigo (lemborexant compound) is an orexin antagonist that acts on the arousal and sleep neural networks of the brain to regulate sleep-wake cycles and is used in the treatment of insomnia characterized by difficulties with sleep.

OTHER

Placebo

The placebo is an inactive sugar pill that looks and tastes identical to the lemborexant pill.

Trial Locations (1)

M5B 1W8

St. Michael's Hospital, Unity Health Toronto, Toronto

All Listed Sponsors
collaborator

University of Toronto

OTHER

collaborator

Centre for Addiction and Mental Health

OTHER

collaborator

Toronto Metropolitan University

OTHER

lead

Unity Health Toronto

OTHER