NCT06837571View on ClinicalTrials.gov

Methadone Dose Monitoring With a Remote Medication Monitor

Not yet recruitingOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

April 26, 2025

Primary Completion Date

May 31, 2025

Study Completion Date

June 30, 2025

Conditions
Methadone ToxicityMethadone OverdosePain, ChronicDrug Metabolism, Poor, CYP2D6-RelatedMetabolism Medication Toxicity
Interventions
DIAGNOSTIC_TEST

Measurement of Methadone in the Interstitial Fluid (ISF) before and after prescribed dose taken ex vivo

Measurement of Methadone and its metabolites in interstitial fluid with Liquid Chromatography - Mass Spectroscopy (LC-MS) and Aptamer based Assay

DRUG

Measurement of Methadone in the Interstitial Fluid before and after prescribed dose taken in vivo

Measurement of Methadone and its metabolites in ISF with LC-MS and RMM

DEVICE

ISF Extraction Device 2

Up to 15 minute periods of continuous ISF collection for analysis

Trial Locations (1)

91945

Synergy, Lemon Grove

Sponsors

Lead Sponsor

Cari Health Inc.
All Listed Sponsors
lead

Cari Health Inc.

OTHER

NCT06837571 - Methadone Dose Monitoring With a Remote Medication Monitor | Biotech Hunter | Biotech Hunter