The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS

NANot yet recruitingINTERVENTIONAL
Enrollment

213

Participants

Timeline

Start Date

March 14, 2025

Primary Completion Date

March 14, 2027

Study Completion Date

March 14, 2027

Conditions
Olfactory DysfunctionChronic Rhinosinusitis
Interventions
DEVICE

Conventional olfactory training device

"Four odorants are used: phenyl ethyl alcohol (PEA): rose, menthol: mint, citronellal: lemon, and eugenol: cloves. Training patients will receive four glass vials. Each contains one odorant (5 mL, soaked in cotton pads to prevent spilling) and is labeled with the name of the odorant.~Budesonide irrigation can effectively target the olfactory cleft area to provide anti-inflammatory effects."

DEVICE

Modified olfactory training device

"The modified olfactory training device is based on the nasal bidirectional drug delivery system. The device uses breathing pressure to create positive pressure, significantly increasing the deposition rate of odors in the olfactory cleft area.~Budesonide irrigation can effectively target the olfactory cleft area to provide anti-inflammatory effects."

DRUG

Budesonide irrigation

Budesonide irrigation can effectively target the olfactory cleft area to provide anti-inflammatory effects.

Trial Locations (1)

100191

Beijing, Beijing

All Listed Sponsors
lead

Peking University Third Hospital

OTHER

NCT06837051 - The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS | Biotech Hunter | Biotech Hunter