524
Participants
Start Date
February 20, 2025
Primary Completion Date
July 31, 2032
Study Completion Date
July 31, 2032
Laparoscopic radical hysterectomy incorporating modified tumor-free techniques
"Thoroughly examine the pelvic and abdominal cavities. Coagulation of the fallopian tubes are recommanded at the beginning of the surgery. The use of uterine manipulator is prohibited. An 8-suture at the uterine fundus is recommended. Insert a trocar 3 cm above the pubic symphysis and suspend the uterus by pulling with a needle holder. Alternative methods are also acceptable. Perform pelvic lymphadenectomy. Conduct radical hysterectomy according to the Q-M classification type C. Before incising the vagina, the upper part of the vagina must be closed (using a cable tie or suture), or the vagina can be incised transvaginally after deflating the pneumoperitoneum. Sterilized distilled water or saline solution (≥1000 mL) is used to irrigate the pelvic cavity. The vaginal stump can be sutured either laparoscopically or transvaginally."
Abdominal radical hysterectomy
At the onset of surgery, comprehensively explore the pelvic and abdominal cavities. If intraperitoneal metastases are identified, radical hysterectomy should be aborted. Perform pelvic lymphadenectomy. After lymph node resection, remove the lymph nodes from the surgical field promptly. Sentinel lymph node mapping and biopsy are not performed in this study. Perform radical hysterectomy according to type C of the Q-M classification. It can be accompanied by or without bilateral salpingo - oophorectomy. For patients who retain their ovaries, bilateral ovarian transposition can be carried out. Before incising the vagina, close the upper segment of the vagina and/or the vaginal stump. This can be achieved using instruments such as a large right - angle clamp or an auricular clamp. Sterilized distilled water or saline solution (≥1000 mL) is used to irrigate the pelvic cavity.
RECRUITING
Peking Union Medical College Hospital, Beijing
RECRUITING
The Second Hospital of Jilin University, Changchun
NOT_YET_RECRUITING
Renji Hospital Affiliated to The Shanghai Jiao Tong University Medical School, Shanghai
NOT_YET_RECRUITING
Zhejiang cancer hospital, Hangzhou
NOT_YET_RECRUITING
Hunan Provincial Maternal and Child Health Care Hospital, Changsha
NOT_YET_RECRUITING
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou
NOT_YET_RECRUITING
Affiliated Hospital of North Sichuan Medical College, Nanchong
NOT_YET_RECRUITING
The Fourth Military Medical University, Xijing Hospital, Xi’an
NOT_YET_RECRUITING
Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Xianyang
NOT_YET_RECRUITING
The First Hospital of Lanzhou University, Lanzhou
NOT_YET_RECRUITING
Cangzhou Central Hospital, Cangzhou
NOT_YET_RECRUITING
The Fourth Hospital of Hebei Medical University, Shijiazhuang
NOT_YET_RECRUITING
Tianjin Central Hospital of Gynecology Obstetrics, Tianjin
Hebei Medical University Fourth Hospital
OTHER
Second Hospital of Jilin University
OTHER
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER
Cangzhou Central Hospital
OTHER
Zhejiang Cancer Hospital
OTHER
Hunan Provincial Maternal and Child Health Care Hospital
OTHER
LanZhou University
OTHER
RenJi Hospital
OTHER
The Fourth Military Medical University, Xijing Hospital
UNKNOWN
Affiliated Hospital of Shanxi University of Traditional Chinese Medicine
UNKNOWN
Affiliated Hospital of North Sichuan Medical College
OTHER
Tianjin Central Hospital of Gynecology Obstetrics
OTHER
Peking Union Medical College Hospital
OTHER