Modified Tumor-free Techniques Operation to Cervical Cancer

NARecruitingINTERVENTIONAL
Enrollment

524

Participants

Timeline

Start Date

February 20, 2025

Primary Completion Date

July 31, 2032

Study Completion Date

July 31, 2032

Conditions
Cervical Cancer Stage IB2
Interventions
PROCEDURE

Laparoscopic radical hysterectomy incorporating modified tumor-free techniques

"Thoroughly examine the pelvic and abdominal cavities. Coagulation of the fallopian tubes are recommanded at the beginning of the surgery. The use of uterine manipulator is prohibited. An 8-suture at the uterine fundus is recommended. Insert a trocar 3 cm above the pubic symphysis and suspend the uterus by pulling with a needle holder. Alternative methods are also acceptable. Perform pelvic lymphadenectomy. Conduct radical hysterectomy according to the Q-M classification type C. Before incising the vagina, the upper part of the vagina must be closed (using a cable tie or suture), or the vagina can be incised transvaginally after deflating the pneumoperitoneum. Sterilized distilled water or saline solution (≥1000 mL) is used to irrigate the pelvic cavity. The vaginal stump can be sutured either laparoscopically or transvaginally."

PROCEDURE

Abdominal radical hysterectomy

At the onset of surgery, comprehensively explore the pelvic and abdominal cavities. If intraperitoneal metastases are identified, radical hysterectomy should be aborted. Perform pelvic lymphadenectomy. After lymph node resection, remove the lymph nodes from the surgical field promptly. Sentinel lymph node mapping and biopsy are not performed in this study. Perform radical hysterectomy according to type C of the Q-M classification. It can be accompanied by or without bilateral salpingo - oophorectomy. For patients who retain their ovaries, bilateral ovarian transposition can be carried out. Before incising the vagina, close the upper segment of the vagina and/or the vaginal stump. This can be achieved using instruments such as a large right - angle clamp or an auricular clamp. Sterilized distilled water or saline solution (≥1000 mL) is used to irrigate the pelvic cavity.

Trial Locations (13)

100079

RECRUITING

Peking Union Medical College Hospital, Beijing

130041

RECRUITING

The Second Hospital of Jilin University, Changchun

200001

NOT_YET_RECRUITING

Renji Hospital Affiliated to The Shanghai Jiao Tong University Medical School, Shanghai

310022

NOT_YET_RECRUITING

Zhejiang cancer hospital, Hangzhou

410000

NOT_YET_RECRUITING

Hunan Provincial Maternal and Child Health Care Hospital, Changsha

510120

NOT_YET_RECRUITING

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

637000

NOT_YET_RECRUITING

Affiliated Hospital of North Sichuan Medical College, Nanchong

710032

NOT_YET_RECRUITING

The Fourth Military Medical University, Xijing Hospital, Xi’an

712000

NOT_YET_RECRUITING

Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Xianyang

730000

NOT_YET_RECRUITING

The First Hospital of Lanzhou University, Lanzhou

061000

NOT_YET_RECRUITING

Cangzhou Central Hospital, Cangzhou

050011

NOT_YET_RECRUITING

The Fourth Hospital of Hebei Medical University, Shijiazhuang

Unknown

NOT_YET_RECRUITING

Tianjin Central Hospital of Gynecology Obstetrics, Tianjin

All Listed Sponsors
collaborator

Hebei Medical University Fourth Hospital

OTHER

collaborator

Second Hospital of Jilin University

OTHER

collaborator

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

collaborator

Cangzhou Central Hospital

OTHER

collaborator

Zhejiang Cancer Hospital

OTHER

collaborator

Hunan Provincial Maternal and Child Health Care Hospital

OTHER

collaborator

LanZhou University

OTHER

collaborator

RenJi Hospital

OTHER

collaborator

The Fourth Military Medical University, Xijing Hospital

UNKNOWN

collaborator

Affiliated Hospital of Shanxi University of Traditional Chinese Medicine

UNKNOWN

collaborator

Affiliated Hospital of North Sichuan Medical College

OTHER

collaborator

Tianjin Central Hospital of Gynecology Obstetrics

OTHER

lead

Peking Union Medical College Hospital

OTHER