Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial

PHASE2RecruitingINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

April 14, 2025

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2029

Conditions
Glioblastoma (GBM)
Interventions
RADIATION

Dose-escalated radiation therapy

Dose-escalated radiation therapy involves higher doses of radiation therapy each day of treatment over the three week course of radiation therapy

RADIATION

Standard hypofractionated radiation

Standard hypofractionated radiation therapy over 3 weeks

Trial Locations (3)

02115

RECRUITING

Brigham and Women's Hospital, Boston

01757

RECRUITING

Dana-Farber Brigham Cancer Center, Milford Hospital, Milford

02190

RECRUITING

Dana-Farber Brigham Cancer Center, South Shore Hospital, South Weymouth

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER