Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder

NANot yet recruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

April 1, 2029

Study Completion Date

August 1, 2029

Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
DEVICE

Active transcranial direct current stimulation

Multifocal transcranial direct current stimulation will be delivered. The anode will be placed over the frontal pole (Fpz, 10-20 electroencephalogram \[EEG\]) and will be surrounded by 5 return electrodes (cathodes). Current will be set at 1.5mA and will be ramped in and out for 30 seconds at the beginning and end of a 20-minute stimulation period.

DEVICE

Sham transcranial direct current stimulation

Multifocal transcranial direct current stimulation will be delivered. The anode will be placed over the frontal pole (Fpz, 10-20 electroencephalogram \[EEG\]) and will be surrounded by 5 return electrodes (cathodes). Current will be set at 1.5mA and will be ramped in and out for 30 seconds at the beginning of a 20-minute period.

Trial Locations (1)

06511

Temple Medical Center, New Haven

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Yale University

OTHER

NCT06834217 - Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder | Biotech Hunter | Biotech Hunter