Prospective Cohort Study Evaluating 18FDG PET-CT for the Early Prediction of the Efficacy of Immunotherapy Associated or Not With Chemotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Broncho-Pulmonary Carcinoma

RecruitingOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

January 27, 2022

Primary Completion Date

May 27, 2028

Study Completion Date

January 27, 2031

Conditions
Carcinoma, Non-Small-Cell Lung (NSCLC)
Interventions
PROCEDURE

FDG-PET

PET scan are performed within 28 days before the start of immunotherapy, then at week 6 and week 12 of follow-up. Various metabolic parameters extracted from the standard PET image (ΔSUVmax, ΔTLG, appearance of new visceral lesion(s)), parametric (metabolic glucose rate (Ki), volume of distribution (VD)) and tumor response based on PERCIST criteria (adapted to immunotherapy) are assessed.

Trial Locations (1)

06189

RECRUITING

Centre Antoine Lacassagne, Nice

All Listed Sponsors
lead

Centre Antoine Lacassagne

OTHER