The Prediction of Recurrence Lumbar Disc Herniation At L5-S1 Level Through Machine Learning Models Based on Endoscopic Discectomy Via the Interlaminar Approach

CompletedOBSERVATIONAL
Enrollment

309

Participants

Timeline

Start Date

January 1, 2020

Primary Completion Date

May 31, 2024

Study Completion Date

November 1, 2024

Conditions
Recurrent Lumbar Disc Herniation
Interventions
DIAGNOSTIC_TEST

VAS Point and Imaging Examination

"This intervention uses a machine learning model to predict the risk of recurrent lumbar disc herniation (rLDH) in patients who have had percutaneous endoscopic interlaminar discectomy (PEID) at the L5-S1 level. The model combines clinical data (e.g., BMI, disease duration, diabetes) and imaging metrics (e.g., posterior disc height index, spinal canal stenosis) to create a personalized risk score, unlike traditional methods that rely on clinical judgment or imaging alone.~Key Features:~Data-Driven Approach: Developed using data from 309 patients for real-world relevance.~Advanced Variable Selection: Identifies eight key predictors using LASSO regression.~Multiple Machine Learning Techniques: Uses algorithms like support vector machine, random forest, and extreme gradient boosting.~Optimized for Clinical Decision-Making: Assists surgeons in personalizing treatment plans to reduce recurrence risk."

Trial Locations (1)

226000

Nantong First People's Hospital, Nantong

All Listed Sponsors
collaborator

Nantong First People's Hospital

OTHER

lead

Jinyu Chen

OTHER

NCT06833099 - The Prediction of Recurrence Lumbar Disc Herniation At L5-S1 Level Through Machine Learning Models Based on Endoscopic Discectomy Via the Interlaminar Approach | Biotech Hunter | Biotech Hunter