Emergence Agitation of Sevoflurane in Pediatric

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

May 1, 2024

Primary Completion Date

November 1, 2024

Study Completion Date

November 1, 2024

Conditions
Emergence Delirium
Interventions
DRUG

we will give the patient 0.1 mg nalbuphine 15 min before the end of the procedure

The study medications will be prepared by the local pharmacy as 10 ml syringes of nalbuphine IV that will be handled to the anesthesiologist in charge in OR room who will be blinded to the nature of the medications used, and study medications will be given 15 minutes before the end of surgical procedure and it will be given slowly for five minutes. . After extubation, patients will be taken to postanesthetic care unit . on arrival vital data will be measured. The anesthesiologist following up the patient will be blinded to the groups. The time of extubation will be defined as zero and after 15 minutes will be defined as one . Assessment of agitation will be done at time zero and time 1 and every fifteen minutes for 30 minutes using paediatric anaesthesia Emergence delirium scale (PAEDS)

DRUG

we will give the patient 0.5 mg dexmedetomidine 15 min before the end of the procedure

The study medications will be prepared by the local pharmacy as 10 ml syringes of dexmedetomidine IV that will be handled to the anesthesiologist in charge in OR room who will be blinded to the nature of the medications used, and study medications will be given 15 minutes before the end of surgical procedure and it will be given slowly for five minutes. . After extubation, patients will be taken to postanesthetic care unit . on arrival vital data will be measured. The anesthesiologist following up the patient will be blinded to the groups. The time of extubation will be defined as zero and after 15 minutes will be defined as one . Assessment of agitation will be done at time zero and time 1 and every fifteen minutes for 30 minutes using pediatric anesthesia Emergence delirium scale (PAEDS) .

Trial Locations (1)

11111

Ainshams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT06830564 - Emergence Agitation of Sevoflurane in Pediatric | Biotech Hunter | Biotech Hunter