Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

December 31, 2026

Conditions
Pertussis (Whooping Cough)
Interventions
BIOLOGICAL

Biological: Bordetella pertussis J820

Intranasal inoculation of Bordetella pertussis J820 in each naris on Day 1 of the study.

All Listed Sponsors
collaborator

Centers for Disease Control and Prevention

FED

lead

Dalhousie University

OTHER