NCT06827002View on ClinicalTrials.gov

Effect of Aqueous Extracts of Cissus Quadrangularis and Dichrostachys Glomerata on GLP-1 Concentration and DPP-4 Activity in Overweight and Obese Adults

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

248

Participants

Timeline

Start Date

February 12, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

January 31, 2026

Conditions
Obesity and OverweightAppetite Regulation
Interventions
DRUG

Dichrostachys glomerata

DGE were procured from Gateway Health Alliances, Fairfield in 400 mg and 300 mg capsules.

DRUG

Cissus quadrangularia

CQR-300® were procured from Gateway Health Alliances, Fairfield in 400 mg and 300 mg capsules.

DRUG

Dextrin

Placebo capsules containing 400 mg of dextrin, looking identical to DGE and CQE were also procured from Gateway Health Alliances, Fairfield, California, USA.

DRUG

Semaglutide (Rybelsus®)

Oral semaglutide (Rybelsus®) was purchased and then repackaged into capsules looking identical to DGE, CQE and placebo capsules.

Trial Locations (1)

00237

University of Yaounde 1, Yaoundé

All Listed Sponsors
collaborator

J & A Oben Foundation

UNKNOWN

lead

University of Yaounde 1

OTHER