Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study

NARecruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

October 15, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Heart Failure with Preserved Ejection Fraction (HFPEF)Heart Failure with Reduced Ejection FractionSarcopenia in ElderlySarcopenic Obesity
Interventions
OTHER

Aerobic eccentric intervention

This arm will participate in a supervised eccentric cycling training program for three months. The intervention will include two training sessions per week in the first month, increasing to three sessions per week in the following two months. Each session will consist of a warm-up (5 minutes), a main training phase (20-30 minutes), and a cool-down (5-10 minutes). The intensity of training will be gradually adjusted to maintain a perceived exertion rating (RPE) between light and moderate with a target heart rate zone (57-76% of HRmax). Pre- and post-training assessments will evaluate physical function through several tests, body composition and anthropometric indices, muscle strength of upper and lower limbs, questionnaires related to the overall health improvement. Finally, participants will also be monitored for daily physical activity through wearable sensors to track mobility and autonomy.

Trial Locations (2)

37131

RECRUITING

University of Verona, Verona

RECRUITING

University of Verona, Verona

All Listed Sponsors
lead

Universita di Verona

OTHER