NCT06826755View on ClinicalTrials.gov

Melatonin Effects on Cardiovascular Disease Mechanisms in the Menopause Transition: A Randomized Clinical Trial

NARecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

May 23, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

January 31, 2027

Conditions
PerimenopauseHypertension
Interventions
DIETARY_SUPPLEMENT

Terry Naturally® melatonin 5mg SR

Participants will take SR melatonin 5mg (or placebo) orally 1 hour before bed, for approximately 12 weeks. The study is comparing the effects of melatonin supplementation vs. placebo on cardiovascular risk measures in perimenopausal women.

DIETARY_SUPPLEMENT

Placebo

Participants will take SR melatonin 5mg (or placebo) orally 1 hour before bed, for approximately 12 weeks. The study is comparing the effects of melatonin supplementation vs. placebo on cardiovascular risk measures in perimenopausal women.

Trial Locations (1)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

Mayo Clinic
All Listed Sponsors
lead

Mayo Clinic

OTHER