NCT06825455View on ClinicalTrials.gov

Allogeneic B7H3 CAR-γδT Cell Therapy for Advanced Solid Tumors

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Advanced Solid TumorsOvarian CancersPeritoneal (metastatic) Cancer
Interventions
DRUG

Fludarabine

Intravenous infusion group:30mg/m2 x 3 days (Day-4\~-2)

DRUG

Cyclophosphamide

Intravenous infusion group:500mg/m2 x 3 days (Day-4\~-2)

BIOLOGICAL

B7H3 CAR-γδT cells

A single infusion of 6.0×107 CAR+ cells, 2.0×108CAR+ cells, and 6.0×108CAR+ cells

Trial Locations (1)

Unknown

Beijing Cancer Hospital, Beijing

All Listed Sponsors
lead

Peking University

OTHER