NCT06824948 - Evaluate the Safety, Tolerance, and Pharmacokinetic Profiles of Timolol Maleate Gel | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 12, 2018

Primary Completion Date

December 12, 2018

Study Completion Date

December 12, 2018

Conditions

Healthy Subjects

Interventions

DRUG

Timolol Maleate Gel

A 2-day washout phase follows 1 dose on Day 1, the subjects are applied with 0.5% timolol maleate gel one time a day during Day 3-Day 12.

DRUG

Placebo

A 2-day washout phase follows 1 dose on Day 1, the subjects are applied with placebo one time a day during Day 3-Day 12.

DRUG

Timolol Maleate Gel

A 2-day washout phase follows 1 dose on Day 1, the subjects are applied with 0.5% timolol maleate gel 2 times a day during Day 3-Day 12.

DRUG

Placebo

A 2-day washout phase follows 1 dose on Day 1, the subjects are applied with placebo 2 times a day during Day 3-Day 12.

DRUG

Timolol Maleate Gel

A 2-day washout phase follows 1 dose on Day 1, the subjects are applied with 0.5% timolol maleate gel 3 times a day during Day 3-Day 12.

DRUG

Placebo

A 2-day washout phase follows 1 dose on Day 1, the subjects are applied with placebo 3 times a day during Day 3-Day 12.

Trial Locations (1)

Shanghai Xuhui District Central Hospital, Shanghai