Can Neoadjuvant Chemoradiotherapy be Ommited in Mid-rectal Cancer

Not yet recruitingOBSERVATIONAL
Enrollment

436

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

August 1, 2030

Study Completion Date

August 1, 2035

Conditions
Mid-Rectal CancerRectal Cancer Stage IIRectal Cancer Stage III
Interventions
OTHER

Total mesorectal excision

Direct surgery without receiving neoadjuvant chemoradiotherapy

OTHER

Neoadjuvant Chemotherapy followed by total mesorectal excision

Neoadjuvant chemoradiotherapy treatment regimens (including conventional chemoradiotherapy/radiotherapy/chemotherapy regimens or total neoadjuvant chemoradiotherapy regimens) before surgery

Trial Locations (5)

34394

Istanbul Health and Technology University, Istanbul

Unknown

Baskent University, Ankara

Memorial sisli Hospital, Istanbul

Acibadem Kent Hospital, Izmir

Dokuz Eylul University, Izmir

All Listed Sponsors
collaborator

Baskent University

OTHER

collaborator

Dokuz Eylul University

OTHER

collaborator

Halic University

OTHER

collaborator

Acibadem Kent Hospital

OTHER

collaborator

Istanbul Health and Technology University

OTHER

lead

Turkish Society of Colon and Rectal Surgery

OTHER