CRIC Combined With MFT for Cardiovascular Adverse Events in Patients With Incomplete Revascularization of CAD

NARecruitingINTERVENTIONAL
Enrollment

3,420

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

January 1, 2028

Study Completion Date

December 30, 2029

Conditions
Coronary Artery Disease
Interventions
DEVICE

chronic remote ischemic conditioning

Using a semi-automated machine, the pressure is increased according to the patient's own blood pressure level (20-40mmHg) when the cuff is pressed, and the pressure is squeezed for 6 minutes per cycle and the rest is 4 minutes, for a total of 4 cycles per cycle.

BEHAVIORAL

Mindfulness Therapy

Participants receive guided mindfulness audio sessions twice daily for \~30 minutes each throughout the perioperative period. Content includes standardized mindfulness practices (e.g., focused attention, body awareness, nonjudgmental observation) designed to reduce anxiety and improve sleep quality.

OTHER

sham CRIC

The pressure was 60mmHg when the cuff was pressurized, and the other modes were the same as those of the CIRC group.

BEHAVIORAL

sham MFT

Sham MFT: Health Education + Relaxation (HER): A time- and attention-matched audio program (twice daily, 30 minutes) delivering perioperative recovery and sleep-hygiene education with passive relaxation (music or simple muscle loosening), excluding mindfulness-specific techniques (no present-moment/nonjudgmental awareness training, no breath-focused meditation, no open monitoring).

Trial Locations (1)

450000

RECRUITING

Fuwai Central China Cardiovascular Hospital, Zhengzhou

All Listed Sponsors
lead

Henan Institute of Cardiovascular Epidemiology

OTHER

NCT06820970 - CRIC Combined With MFT for Cardiovascular Adverse Events in Patients With Incomplete Revascularization of CAD | Biotech Hunter | Biotech Hunter