Inhaled Polymyxin E to Prevent VAP

NANot yet recruitingINTERVENTIONAL
Enrollment

434

Participants

Timeline

Start Date

February 1, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

June 30, 2028

Conditions
Ventilator-Associated Pneumonia (VAP)Inha'le'd
Interventions
DRUG

Inhaled Placebo

Inhalation of drugs was started within 24 hours after the screening of patients. Both groups inhaled with vibrating mesh spray twice a day for 3 days. The NS group inhaled with normal saline .

DRUG

inhaled corticosteroids and other asthma drugs

Inhalation of drugs was started within 24 hours after the screening of patients. Both groups used vibrating mesh spray twice a day for 3 days. The Polymyxin E group inhaled polymyxin, 75 mg bid.

All Listed Sponsors
lead

Southeast University, China

OTHER

NCT06819462 - Inhaled Polymyxin E to Prevent VAP | Biotech Hunter | Biotech Hunter