Reconstruction of Cervical Lymphatic System During Head and Neck Squamous Cell Carcinoma Surgery

NANot yet recruitingINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

March 20, 2025

Primary Completion Date

January 31, 2027

Study Completion Date

December 31, 2027

Conditions
Head and Neck Squamous Cell CarcinomaLymphedema, SecondaryNeck Lymph DissectionVascularized Lymph Node Transplantation
Interventions
PROCEDURE

Vascularized lymphatic transplantation

"Preoperative ultrasonography was performed to check the distribution, quantity and size of axillary lymph nodes. During the operation, methylene blue was injected subcutaneously into the elbow fossa to make the axillary lymph nodes in area B and D chromogenic, and avoid damage to the arm drainage lymph nodes.~Adjusting the flap design according to the size of the defect. The perforating branches of lymphoid tissue in areas A and C of grade I were located about 3-5cm above the perforating branches of the skin, and moved towards the thoracic side to the lymphatic adipose tissue. Finally, the pedicle of the thoracic dorsal artery was separated, and the blood transport of the flap and the lymphatic adipose tissue was examined by fluorescence imaging and other methods. The lymphoid adipose tissue was placed in the neck area I and II, and fixed by suture. The arteriovenous microvessels in the thoracic dorsal were anastomosed to the vessels in the receiving area of neck."

Trial Locations (1)

510120

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

NCT06815705 - Reconstruction of Cervical Lymphatic System During Head and Neck Squamous Cell Carcinoma Surgery | Biotech Hunter | Biotech Hunter