Neuromodulation After Spinal Cord Injury to Improve Limb Function

Intermittent theta burst stimulation (iTBS) will be utilized since they have been reported to have a cortical neuromodulatory effect. The iTBS protocol will be applied over primary motor cortex to investigate its effect on corticospinal excitability and functional outcome. Theta burst stimulation (TBS) consists of bursts of pulses containing 3 pulses at 50 Hz (3 pulses per second) repeated at 200 ms intervals (5 Hz). During iTBS, a 2 second train of TBS is repeated every 10 seconds (600 pulses in 190 seconds).

Sham iTBS protocols will be applied with the same parameters as in iTBS protocol. However, sham coil will be used.

The motor training will be focused on participant's hand motor function such as grasping function.