Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications

NARecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

February 10, 2025

Primary Completion Date

July 28, 2025

Study Completion Date

August 28, 2025

Conditions
PrematurePlacental Transfusion
Interventions
PROCEDURE

intact umbilical milking

"Umbilical cord milking will be performed by holding the newborn at or~∼20 cm below the level of the placenta. The cord will be pinched between 2 fingers as close to the placenta as possible and milked toward the infant over a 2-second duration. The cord will then be released and allowed to refill with blood for a brief 1- to 2-second pause between each milking motion. This will be repeated for 2-4 times. After completion, the cord will be clamped, and the neonate will be handed to the resuscitation team."

PROCEDURE

cut umbilical milking

Another technique, used more often in Asia, involves clamping and cutting a long segment of the umbilical cord immediately at birth and passing the baby and the long cord to the pediatric provider, called C-UCM untwists the cord and milks the entire contents into the baby. Milking the cord 2-3 times before clamping may produce a similar placental transfusion as C-UCM

PROCEDURE

Delayed cord clamping

Infants placed on the maternal abdomen or at the introitus below the level of placenta and waiting at least 30- to 60-second before clamping the cord.

Trial Locations (1)

0325

RECRUITING

Marwa Mohamed Farag, Alexandria

All Listed Sponsors
lead

Alexandria University

OTHER