Short Course Radiation Treatment for Patients With Primary or Locally Recurrent Retroperitoneal Sarcoma Prior to Surgery

PHASE1RecruitingINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

May 29, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Retroperitoneal Sarcoma
Interventions
RADIATION

Radiation Therapy

In this study, patients will receive a hypofractionated course of radiation therapy of 2.85 Gy x 15 fractions (42.75 Gy). If there are 2 or more patients with dose-limiting toxicities, the radiation course will be de-escalated to 2.7 Gy x 15 fractions (40.5 Gy).

RADIATION

Hypofractionationed Radiation Therapy

This group is receiving hypofractionated radiation therapy (shorter course of RT)

Trial Locations (1)

02446

RECRUITING

Brigham and Women's Hospital / Dana Farber Cancer Institute, Boston

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER