Intravenous Versus Perineural Ondansetron for Laparoscopic Sleeve Gastrectomy

NARecruitingINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

February 16, 2025

Primary Completion Date

March 16, 2026

Study Completion Date

March 17, 2026

Conditions
OndansetronLaparoscopicGastrectomy
Interventions
DRUG

Perineural ondansetron

Para-gastric autonomic neural blockade will be performed (after separation of the stomach and performing the methylene blue leak test) using 20 ml solution containing 18 ml bupivacaine 0.5% plus 2 ml (4 mg) ondansetron. At the same time, 15 ml saline will be injected slowly IV over 15 minutes.

DRUG

Intravenous ondansetron

Para-gastric autonomic neural blockade will be performed (after separation of the stomach and performing the methylene blue leak test) using 20 ml solution containing 18 ml bupivacaine 0.5% plus 2 ml saline. At the same time, 4 mg (2 ml) ondansetron mixed with 13 ml saline (total 15 ml) will be slowly injected IV over 15 minutes.

Trial Locations (1)

31527

RECRUITING

Tanta University Hospitals, Tanta

All Listed Sponsors
lead

Tanta University

OTHER