Psilocybin on Brain Mechanisms of Motivation in OUD

PHASE2Not yet recruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

May 1, 2026

Study Completion Date

May 1, 2026

Conditions

Opioid Use Disorder

Interventions

DRUG

Psilocybin (high dose)

PEX010 is the psilocybin produced by Filament

DRUG

psilocybin (low dose)

1mg psilocybin, produced by Filament

Trial Locations (1)

University of Pennsylvania, Philadelphia

All Listed Sponsors

lead

Anna Rose Childress, Ph.D.

OTHER