Complete Closure After Endoscopic Mucosal Resection of Large Non-Pedunculated Colorectal Polyps

Endoscopists will use at least one new generation closure device to approximate the healthy mucosal surrounding the submucosal defect to ensure complete defect closure. Adequate apposition of the mucosal defect margins will be achieved when no visible submucosal areas \>3 mm along the closure line are present.

After performing EMR with thermal ablation, prophylactic defect closure will not be performed.