A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

PHASE3RecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

September 13, 2025

Primary Completion Date

July 17, 2027

Study Completion Date

July 30, 2027

Conditions
Interstitial Lung DiseasesSystemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
Interventions
DRUG

Nerandomilast

Nerandomilast

DRUG

Placebo matching nerandomilast

Placebo matching nerandomilast

Trial Locations (156)

1090

NOT_YET_RECRUITING

AKH - Medical University of Vienna, Vienna

1205

NOT_YET_RECRUITING

Hopitaux Universitaires de Geneve (HUG), Geneva

1478

NOT_YET_RECRUITING

Akershus Universitetssykehus HF, Nordbyhagen

2000

NOT_YET_RECRUITING

Neuchatel Hospital Network, Neuchâtel

2010

NOT_YET_RECRUITING

St Vincent's Hospital Sydney, Darlinghurst

2050

NOT_YET_RECRUITING

Royal Prince Alfred Hospital, Camperdown, Sydney

3015

NOT_YET_RECRUITING

Erasmus Medisch Centrum-ROTTERDAM-50697, Rotterdam

3084

NOT_YET_RECRUITING

Austin Hospital, Heidelberg

3500

NOT_YET_RECRUITING

Krems University Hospital, Krems

4031

NOT_YET_RECRUITING

Universitätsspital Basel, Basel

4032

NOT_YET_RECRUITING

The Prince Charles Hospital, Chermside

4600

NOT_YET_RECRUITING

Klinikum Wels - Grieskirchen GmbH, Wels

6150

NOT_YET_RECRUITING

Fiona Stanley Hospital, Murdoch

8091

NOT_YET_RECRUITING

University Hospital Zurich, Zurich

9007

NOT_YET_RECRUITING

Kantonsspital St.Gallen, Sankt Gallen

10017

NOT_YET_RECRUITING

NYU Langone Health, New York

10024

NOT_YET_RECRUITING

Columbia University Medical Center-New York Presbyterian Hospital, New York

10117

NOT_YET_RECRUITING

Charite Universitätsmedizin Berlin KöR, Berlin

11021

NOT_YET_RECRUITING

Northwell Health, Great Neck

13125

NOT_YET_RECRUITING

Immanuel-Krankenhaus GmbH, Berlin

13620

NOT_YET_RECRUITING

Seoul National University Bundang Hospital, Seongnam

14004

NOT_YET_RECRUITING

Hospital Universitario Reina Sofía-Córdoba-40500, Córdoba

14080

NOT_YET_RECRUITING

Inst Nac de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City

15213

NOT_YET_RECRUITING

University of Pittsburgh Medical Center, Pittsburgh

15706

NOT_YET_RECRUITING

Hospital Clínico de Santiago, Santiago de Compostela

19140

NOT_YET_RECRUITING

Temple Lung Center, Philadelphia

20122

NOT_YET_RECRUITING

Fondazione IRCCS Ca'Granda-Ospedale Maggiore Policlinico, Milan

20132

NOT_YET_RECRUITING

IRCCS San Raffaele, Milan

21005

NOT_YET_RECRUITING

Hospital Juan Ramón Jimenez, Huelva

23538

NOT_YET_RECRUITING

Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck

25123

NOT_YET_RECRUITING

ASST degli Spedali Civili di Brescia, Brescia

25801

NOT_YET_RECRUITING

Rheumatology and Pulmonary Clinic, Beckley

27100

NOT_YET_RECRUITING

Fondazione IRCCS Policlinico S. Matteo, Pavia

27103

NOT_YET_RECRUITING

Southeastern Research Center-Winston Salem-69289, Winston-Salem

28034

NOT_YET_RECRUITING

Hospital Universitario Ramon Y Cajal, Madrid

28040

NOT_YET_RECRUITING

Fundación Jiménez Díaz, Madrid

28041

NOT_YET_RECRUITING

Hospital Universitario 12 de Octubre, Madrid

28144

NOT_YET_RECRUITING

Onsite Clinical Solutions, Salisbury

30052

NOT_YET_RECRUITING

Tianjin Medical University General Hospital, Tianjin

30309

NOT_YET_RECRUITING

Piedmont Hospital, Atlanta

30625

NOT_YET_RECRUITING

Medizinische Hochschule Hannover, Hanover

30912

NOT_YET_RECRUITING

Augusta University, Augusta

31020

NOT_YET_RECRUITING

Investigacion y Biomedicina de Chihuahua S.C., Chihuahua City

31059

NOT_YET_RECRUITING

HOP Rangueil, Toulouse

32429

NOT_YET_RECRUITING

Johannes Wesling Klinikum Minden, Minden

33076

NOT_YET_RECRUITING

HOP Pellegrin, Bordeaux

33125

NOT_YET_RECRUITING

Miami VA Healthcare System, Miami

33511

NOT_YET_RECRUITING

Meris Clinical Research-Brandon-69466, Brandon

35128

NOT_YET_RECRUITING

Università degli Studi Padova, Padua

35203

NOT_YET_RECRUITING

HOP Sud, Rennes

35294

NOT_YET_RECRUITING

University of Alabama at Birmingham, Birmingham

36312

NOT_YET_RECRUITING

Complejo Hospitalario Universitario de Vigo, Vigo

38126

NOT_YET_RECRUITING

Städtisches Klinikum Braunschweig gGmbH, Braunschweig

39245

NOT_YET_RECRUITING

Helios Fachklinik Vogelsang-Gommern GmbH, Gommern

40225

NOT_YET_RECRUITING

Universitätsklinikum Düsseldorf, Düsseldorf

41009

NOT_YET_RECRUITING

Hospital Virgen Macarena, Seville

41013

NOT_YET_RECRUITING

Hospital Virgen del Rocío, Seville

41100

NOT_YET_RECRUITING

Azienda Ospedaliera Policlinico di Modena, Modena

44160

NOT_YET_RECRUITING

Centro Integral en Reumatologia, SA. de CV., Guadalajara

44195

NOT_YET_RECRUITING

Cleveland Clinic, Cleveland

44649

NOT_YET_RECRUITING

St. Elisabeth Gruppe GmbH Katholische Kliniken Rhein-Ruhr, Herne

45239

NOT_YET_RECRUITING

Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH, Essen

46017

NOT_YET_RECRUITING

Hospital Dr. Peset, Valencia

48013

NOT_YET_RECRUITING

Hospital de Basurto, Bilbao

49933

NOT_YET_RECRUITING

HOP d'Angers, Angers

50134

NOT_YET_RECRUITING

A. O. Universitaria Careggi, Frienze

51149

NOT_YET_RECRUITING

Krankenhaus Porz am Rhein gGmbH, Cologne

53127

NOT_YET_RECRUITING

Universitätsklinikum Bonn AöR, Bonn

53792

NOT_YET_RECRUITING

University of Wisconsin, Madison

55455

NOT_YET_RECRUITING

University of Minnesota, Minneapolis

55905

NOT_YET_RECRUITING

Mayo Clinic, Rochester

59037

NOT_YET_RECRUITING

HOP Claude Huriez, Lille

60201

NOT_YET_RECRUITING

Evanston Hospital, Evanston

60611

NOT_YET_RECRUITING

Northwestern University, Chicago

60637

NOT_YET_RECRUITING

University of Chicago, Chicago

64460

NOT_YET_RECRUITING

Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey

66160

NOT_YET_RECRUITING

University of Kansas Medical Center, Kansas City

67091

NOT_YET_RECRUITING

HOP Civil, Strasbourg

70112

NOT_YET_RECRUITING

LSU Health Sciences Center, New Orleans

73230

NOT_YET_RECRUITING

medius Kliniken gGmbH, Kirchheim unter Teck

75014

NOT_YET_RECRUITING

HOP Cochin, Paris

75018

NOT_YET_RECRUITING

HOP Bichat, Paris

77030

NOT_YET_RECRUITING

The University of Texas Health Science Center at Houston, Houston

78229

NOT_YET_RECRUITING

University of Texas Health Science Center at San Antonio, San Antonio

78464

NOT_YET_RECRUITING

Klinikum Konstanz, Konstanz

79106

NOT_YET_RECRUITING

Universitätsklinikum Freiburg, Freiburg im Breisgau

80206

RECRUITING

National Jewish Health, Denver

80336

NOT_YET_RECRUITING

Klinikum der Universität München AÖR, München

84108

NOT_YET_RECRUITING

University of Utah Health Sciences Center, Salt Lake City

85259

NOT_YET_RECRUITING

Mayo Clinic-Arizona, Scottsdale

90095

NOT_YET_RECRUITING

University of California Los Angeles, Los Angeles

91054

NOT_YET_RECRUITING

Universitätsklinikum Erlangen, Erlangen

92108

NOT_YET_RECRUITING

Paradigm Clinical Research - San Diego, San Diego

93049

NOT_YET_RECRUITING

Krankenhaus Barmherzige Brüder Regensburg, Regensburg

97070

NOT_YET_RECRUITING

Medical Care & Research SA de CV, Mérida

100020

NOT_YET_RECRUITING

Beijing Chao-Yang Hospital, Beijing

100029

NOT_YET_RECRUITING

China-Japan Friendship Hospital, Beijing

100730

NOT_YET_RECRUITING

Peking Union Medical College Hospital, Beijing

200040

NOT_YET_RECRUITING

Huashan Hospital, Fudan University, Shanghai

310003

NOT_YET_RECRUITING

The First Affiliated Hospital, Zhejiang University, Hangzhou

310009

NOT_YET_RECRUITING

The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou

330006

NOT_YET_RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

361003

NOT_YET_RECRUITING

First Affiliated Hospital of Xiamen University, Xiamen

412007

NOT_YET_RECRUITING

Zhuzhou Central Hospital, Zhuzhou

430022

NOT_YET_RECRUITING

Wuhan Union Hospital, Wuhan

430030

NOT_YET_RECRUITING

Tongji Hospital Affiliated Tongji Medical College Huazhong University of S & T, Wuhan

471000

NOT_YET_RECRUITING

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang

510080

RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

610041

NOT_YET_RECRUITING

West China Hospital of Sichuan University, Chengdu

610072

NOT_YET_RECRUITING

People's Hospital of Sichuan Province, Chengdu

999078

NOT_YET_RECRUITING

University Hospital_Macau University of Science and Technology, Macau

06510

NOT_YET_RECRUITING

Yale University School of Medicine, New Haven

02114

NOT_YET_RECRUITING

Massachusetts General Hospital, Boston

02115

NOT_YET_RECRUITING

Brigham and Women's Hospital, Boston

68198-1230

NOT_YET_RECRUITING

University of Nebraska Medical Center, Omaha

Unknown

NOT_YET_RECRUITING

"Gesundheit Nord gGmbH , Klinikverbund Bremen"

00161

NOT_YET_RECRUITING

AOU Policlinico Umberto I, Roma

470-1192

NOT_YET_RECRUITING

Fujita Health University Hospital, Aichi, Toyoake

807-8556

NOT_YET_RECRUITING

Hospital of the University of Occupational and Environmental Health, Fukuoka, Kitakyushu

734-8551

NOT_YET_RECRUITING

Hiroshima University Hospital, Hiroshima, Hiroshima

060-8543

NOT_YET_RECRUITING

Sapporo Medical University Hospital, Hokkaido, Sapporo

060-8648

NOT_YET_RECRUITING

Hokkaido University Hospital, Hokkaido, Sapporo

761-0793

NOT_YET_RECRUITING

Kagawa University Hospital, Kagawa, Kita-gun

216-8511

NOT_YET_RECRUITING

St. Marianna University Hospital, Kanagawa, Kawasaki

252-0375

NOT_YET_RECRUITING

Kitasato University Hospital, Kanagawa, Sagamihara

606-8507

NOT_YET_RECRUITING

Kyoto University Hospital, Kyoto, Kyoto

852-8501

NOT_YET_RECRUITING

Nagasaki University Hospital, Nagasaki, Nagasaki

569-8686

NOT_YET_RECRUITING

Osaka Medical and Pharmaceutical University Hospital, Osaka, Takatsuki

350-0495

NOT_YET_RECRUITING

Saitama Medical University Hospital, Saitama, Iruma-gun

113-8431

NOT_YET_RECRUITING

Juntendo University Hospital, Tokyo, Bunkyo-Ku

113-8603

NOT_YET_RECRUITING

Nippon Medical School Hospital, Tokyo, Bunkyo-ku

160-8582

NOT_YET_RECRUITING

Keio University Hospital, Tokyo, Shinjuku-ku

03650

NOT_YET_RECRUITING

Soltmed Smo, Mexico City

06700

NOT_YET_RECRUITING

CITER Centro de Investigación y Tratamiento de las Enfermedades Reumaticas SA de CV, Mexico City

6419 PC

NOT_YET_RECRUITING

Zuyderland Medisch Centrum, Heerlen

3435 CM

NOT_YET_RECRUITING

St. Antonius ziekenhuis, locatie Nieuwegein, Nieuwegein

N-3710

NOT_YET_RECRUITING

Sykehuset Telemark HF, Avd. Skien, Skien

00917

NOT_YET_RECRUITING

GCM Medical Group, PSC, San Juan

02447

NOT_YET_RECRUITING

Kyung Hee University Hospital, Seoul

03080

NOT_YET_RECRUITING

Seoul National University Hospital, Seoul

04401

NOT_YET_RECRUITING

Soonchunhyang University Hospital Seoul, Seoul

08026

NOT_YET_RECRUITING

Hospital Santa Creu i Sant Pau, Barcelona

08035

NOT_YET_RECRUITING

Hospital Universitari Vall D Hebron, Barcelona

08907

NOT_YET_RECRUITING

Hospital de Bellvitge, L'Hospitalet de Llobregat

CH-5001

NOT_YET_RECRUITING

Cantonal Hospital of Aarau, Aarau

BT41 2RL

NOT_YET_RECRUITING

Antrim Area Hospital, Antrim

BA1 3NG

NOT_YET_RECRUITING

Royal United Hospital, Bath, Bath

B9 5SS

NOT_YET_RECRUITING

Heartlands Hospital, Birmingham

SW17 0QT

RECRUITING

St George's Hospital-London-26733, London

SW3 6NP

NOT_YET_RECRUITING

Royal Brompton Hospital, London

WC1E 6BT

NOT_YET_RECRUITING

University College Hospital, London

BT47 6SB

NOT_YET_RECRUITING

Altnagelvin Area Hospital, Londonderry

PR2 9HT

NOT_YET_RECRUITING

NIHR Lancashire Clinical Research Facility, Preston

S10 2JF

NOT_YET_RECRUITING

Royal Hallamshire Hospital, Sheffield

TR1 3LJ

NOT_YET_RECRUITING

Royal Cornwall Hospital, Truro

SS0 0RY

NOT_YET_RECRUITING

Southend University Hospital, Westcliffe-on-Sea

Sponsors
All Listed Sponsors
lead

Boehringer Ingelheim

INDUSTRY

NCT06806592 - A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases | Biotech Hunter | Biotech Hunter